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Effect of "Supporting Kidney to Eliminate Turbid Fluid" on Routine Indexes in Rats with Chronic Renal Failure
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DOI   10.11656/j.issn.1672-1519.2005.02.08
Key Words   Method of supporting kidney to eliminate turbid fluid";chronic renal failure;TCM treatment;experimental study
Author NameAffiliation
LI Guo-xia Tianjin University of TCM, Tianjin 300193, China 
HUANG Wen-zheng 天津中医学院第一附属医院 天津300193 
HE Yong-sheng 天津中医学院第一附属医院 天津300193 
Abstract
    [Objective] To observe the therapeutic effect of Fushen Jiangzhuo supporting kidney to eliminate turbid fluid on chronic renal failure CRF in rats. [Methods] CRF was established in rats by resection of 5/6 kidney. The changes of urinary protein,serum creatinine SCr,blood urea nitrogen BUN,plasma arterial matriuretic polypeptide ANP,aldosterone ALDOST,serum total cholesterol,triglyceride,serum albumin,total protein,metabolism of calcium and phosphorus, hemoglobin serum T3,T4,blood pressure etc were observed. [Results] This therapy could obviously reduce the quantity of urinary protein P<0.01,decrease SCr and BUN level P<0.01,improve the renal function,decrease level of plasma ANP,ALD and blood lipid P<0.01,improve hypoproteinemia P<0.01,regulate imbalance of calcium and phosphorus metabolism P<0.01,correct anemia P<0.05,reduce serum T3,T4 level P<0.01 and reduce blood pressure P<0.01. [Conclusion] "Method of supporting kidney to eliminate turbid fluid" has marked therapeutic effect on chronic renal failure.

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