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| Clinical Study on Relativity between Disfunction of Kidney for Activation of Qi and Renal Tubule Pathological Injury |
| Hits 1650 Download times 1914 Received:February 02, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2005.02.14 |
| Key Words
disfunction of kidney for activation of Qi;chronic renal disease;renal tubule pathological injury;clinical study |
| Author Name | Affiliation | | WANG Yao-guang | The First Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | ZHANG Bo-li | The First Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | ZHANG Lin | The First Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | 施伯安 | The First Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | 庞雅娟 | 天津中医学院 天津300193 |
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| Abstract
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| [Objective] To study the relativity between syndromes of disfunction of the kidney for the activation of Qi and the pathological injury of renal tubule in chronic renal disease. [Methods] Eight cases of chronic nephritis (nephrotic syndrome) with syndrome of deficiency of both spleen and kidney and disfunction of kidney for activation of Qi were observed clinically. Six cases with other syndromes served as control. Amount of urine in 24 hours,N-acetyl-D-glucosaminidase NAG,galactocyl GAL and the changes of pathological injury in renal tubule were compared between groups. [Results] The amount of urine in 24 hours in treatment group was less obviously than that of control group. The quantity of the urinary protein in 24 hours was increased significantly. The urine NAG was enhanced more obviously than that of control group. The renal tubule pathological injury in this group was characterized as epithelium granule degeneration of renal tubule,renal tubule cystic dilatation,protein cast,focal atrophy. Mild to moderate degree of pathologic changes existed mostly in renal tubule and there was a significant difference compared to control group. [Conclusion] The disfunction of kidney for activation of Qi is related to renal tubule pathological injury morphologically. Pathophysioilogically it related to excessive compensation,excessive protein load,decreased reabsorption function of renal tubule. |
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