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| Detection of TNF-α, LTB4 in Bronchoalveolar Lavage Fluid in Rat with Qi Deficiency of Lung |
| Hits 1259 Download times 1519 Received:March 06, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2005.03.25 |
| Key Words
lung qi deficiency syndrome;Tumor Necrosis Factor alpha (TNF-α);leukotriene B4(LTB4) |
| Author Name | Affiliation | | LI Ze-geng | The First Affiliated Hospital to Anhui College of Traditional Chinese Medicine, Hefei 230031, China | | ZHANG Jie-gen | The First Affiliated Hospital to Anhui College of Traditional Chinese Medicine, Hefei 230031, China | | PENG Bo | The First Affiliated Hospital to Anhui College of Traditional Chinese Medicine, Hefei 230031, China | | 张念志 | The First Affiliated Hospital to Anhui College of Traditional Chinese Medicine, Hefei 230031, China | | 韩明向 | The First Affiliated Hospital to Anhui College of Traditional Chinese Medicine, Hefei 230031, China |
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| Abstract
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| [Objective] To detect the levels of TNFα and LTB4 in bronchoalveolar lavage fluid of rat with Qi deficiency of lung,and to explore the probable role in The pathogenesis of TNF-α and LTB4. [Methods] Rat with Qi deficiency of lung was induced by repeat intranasal infecting of klebsiella pneumoniae twice a week. Levels of TNF-α and LTB4 in bronchoalveolar lavage fluid of two groups were measured by ELISA. [Results] Levels of TNF-α, LTB4 in the model group were significantly higher than that in normal group. [Conclusion] TNF-α,LTB4 may involve in the chronic inflammation changes in respiratory tract in qi deficiency of lung and may contribute to the pathogenesis of qi deficiency of lung. |
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