| [Objective] To study the clinical effect of Bushenyisui(tonifuing kidney and benefiting marrow) on chronic aregenerative anemia.[Methods] Sixty patients were divided randomly into therapy group(forty patients) and control group(twenty patients).The therapy group was divided into deficiency of kidney yin,deficiency of kidney yang,deficiency of kidney yin and yang again and was given Bushenyisui Ⅰ,Bushenyisui Ⅱ,Bushenyisui Ⅲ respectively.The course of treatment was six months.The control group was given Stanozolol and Securinine.[Result] The total effective rate of therapy group was 77.5%,in which eight patients were cured basically,twelve patients relieved,eleven patients improved obviously.The total effective rate of control group was 60.0%,of which two patients were cured basically,four patients relieved,six patients improved obviously.There was marked difference between both groups(P<0.05).The therapy group was superior to the control group in the improvement of syndrome,elevation of Hb,PLT,increasing of IL-3 level and decreasing of TNF-α,IFN-γ level.[Conclusion] The Bushenyisui method has a better clinical effect on chronic aregenerative anemia.The Bushenyisui method may improve TCM syndrome,peripheral blood hemogram and improve the secretion of hematopoietic cell-regulating factors. |
