Key Words
stress;ulcer index;qi activity disturbance;emotion pathopoiesis;Xinshen 1
Author Name
Affiliation
LIU Jin-ping
BO Min-min
LI Hui-ji
Abstract
[Objective] To explore the pathogenesis of stress ulceration in TCM.[Methods] The stress ulceration in rats was induced by water immersion and immobilization.Sixty rats were divided randomly into five groups,including normal group,model group,Xinshen 1 group,ranitidine group and alprazolam group.The intervention of different medicines on stress ulceration in rats was observed.[Result] There was a marked difference of ulcer index of gastric mucosa and pH value between groups.The ulcer index of Xinshen 1 group was obviously lower than the model group.But the pH value was similar in the Xinshen 1 group and model group.[Conclusion] Xinshen 1 tablet may promote qi and activate blood circulation,send down the abnormal ascending qi and disperse accumulation of pathogen to prevent the occurrence of stress ulceration.The basic pathogenesis of stress ulceration was disturbance of qi activity.
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