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Influence of Tongjingning Granula on Serum β-EP in patients with Primary Dysmenorrhea:Report of 120 Cases
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DOI   10.11656/j.issn.1672-1519.2005.05.28
Key Words   Tongjingning granula of TCD;primary dysmenorrhea;ovarian hormone E2、P;β-ET
Author NameAffiliation
SONG Zhuo-min Tianjin University of TCM, Tianjin 300193, China 
XIU Shu-li Tianjin University of TCM, Tianjin 300193, China 
LUO Mei-yu 天津中医学院第一附属医院, 天津, 300193 
孙淑珍 天津中医学院第二附属医院, 天津, 300150 
哈孝贤 Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To explore the therapeutic mechanism of Tongjingning granula in primary dysmenorrhea PD. [Methods] 120 patients with PD in treatment group were administrated with Tongjingning granula.40 patients with PD in control were administrated with aspirin.In a part of patients the content of serum estrogen E2 and progestogen P in the middle and last period of corepus luteum,β.endorphine β.ET in the midluteal phase and at menstruation were determined. [Result] The curative effect of treatment group was obviously better than that of control group P<0.01.The rate of significant recovery and improvement in treatment group was significantly better than that in control group P<0.01.The E2 level of treatment group was obviously decreased P<0.01.But the P and β.ET level of treatment group obviously increased P<0.01. [Conclusion] Tongjingning granula may regulate ovarian hormone and β.ET level,adjust the mind and emotion,promote the homeostatic equilibrium of organism and consolidate curative effect.

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