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| Protective Effect on Cardiac Muscle in the Transduction Pathway of Protein Kinase C by using Sal B Accommodation in Advanc |
| Hits 2150 Download times 1854 Received:April 10, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2005.05.29 |
| Key Words
the accommodation in advance of Sal B;cardiac muscle cell;protein kinase C |
| Author Name | Affiliation | | DU Rong | Tianjin University of TCM, Tianjin 300193, China | | ZHANG Meng | Tianjin University of TCM, Tianjin 300193, China | | GUO Li-ping | 天津中医学院第一附属医院, 天津, 300193 | | 高秀梅 | Tianjin University of TCM, Tianjin 300193, China | | 商洪才 | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To discuss on Sal B protective effect pathway on cardiac muscle cell against injury due to hypoxia. [Methods] To observe the Sal B effect on cardiac muscle in the pathway of protein kinase C PKC.To discuss on the mechanism of cell protection about Sal B.To establish the CM injury model due to hypoxia and oxygen.recovery by using PKC depressantia. [Result] The accommodation in advance of Sal B may produce the protective effect of pre.adapting sample.The Sal B can promote the effect recovery of hypoxia preconditioning HPC. [Conclusion] The accommodation in advance of Sal B and HPC had similarly cell protection effect.The Sal B may enhance the toleration of injury due to hypoxia and oxygen.recovery by activating protein kinase C pathway in the later time. |
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