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| Influence of Acupuncture on Epicardial Monophasic Action Potential in vivo in Dog with Myocardial Infarction |
| Hits 1684 Download times 1528 Received:August 09, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2005.06.20 |
| Key Words
acupuncture;acute myocardial infarction;dog;epicardial monophasic action potential |
| Author Name | Affiliation | | LIU Xin-qiao | The First Affiliated Hospital of Tianjin Unversity of TCM, Tianjin 100193, china | | LU Shao-qiang | The First Affiliated Hospital of Tianjin Unversity of TCM, Tianjin 100193, china | | LUO Li | The First Affiliated Hospital of Tianjin Unversity of TCM, Tianjin 100193, china |
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| Abstract
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| [Objective] To explore the treatment mechanism of acupuncture on cardiac arrhythmia in animals on the basis of satisfied curative effect by acupuncture in treating cardiac infarction complicated with cardiac arrhythmia clinically.[Method] The experimental animals were divided randomly into acupuncture group and control group. Acute myocardial infarction was induced by ligation of anterior descending coronary artery.[Results] The monophasic action potential amplitude (MAPA) in the region of ischemic cardiac cells in infarcted animals in the acupuncture group increased much more than that in control group after giving acupuncture of NEI GUAN (P6),SAN YIN JIAO(SP6) and SHEN MEN(H7). The monophasic action potential duration (MAPD) in each time interval developed into the almost normal monophasic action potential of epicardium. The second phase platform and the third phase slope rate recovered at some extent.[Conclusion] The acupuncture may improve the whole course of monophasic action potential of depolarization and repolarization and relieve ischemia and anoxemia of cardiac muscle at different extent. The mechanism of acupuncture maybe related with the increasing volume of blood flow of coronary artery and the association of cardiac muscle cell,reducing the resisting power,enhancing the responsiveness of fast pathway and improving the stability of cardiac cytomembrane |
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