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| Influence of Xinshen Formula No.5 on Cardiac Muscle Ultrastructure in Rats with Electric Irritation |
| Hits 1984 Download times 1647 Received:March 03, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2005.06.29 |
| Key Words
Xinshen formula No.5;electric irritation;cardiac muscle ultrastructure |
| Author Name | Affiliation | | YANG You-xin | Tianjin University of TCM, Tianjin 300193, China | | WU Cheng | 天津中医药研究院, 天津, 300020 | | ZHANG Shi-lin | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To explore the relationship between electric stress and the pathogenesis of coronary heart disease and the therapeutic effect of the Xinshen formula.No.5.[Methods] Seventy-two rats were divided into 6 groups:control group,irritation only group,hyperliposis group,hyperliposis and irritation group,hyperliposis,irritation and Chinese herbs group,Western medicine,hyperliposis and irritation group. They were given electric irritation,hyperpiposis food,electric irritation and hyperliposis food,the Xinshen formula No.5 and isosorbide dinitrate respectively. The changes of cardiac muscle ultrastructure were observed three months after breeding.[Results] The change in electric irritation and hyperliposis group was the most obvious. They were followed by irritation group,hyperliposis group. The Xinshen formula No.5 and isosorbide dinitrate could obviously improve this changes.[Conclusion] The Xinshen formula No.5 may prevent and cure the coronary heart disease induced by stress. |
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