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| Influence of Jiuxin Capsule on Expression of Adhesion Factors in Damaged Endothelial Cells |
| Hits 1505 Download times 1684 Received:May 20, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2005.06.31 |
| Key Words
Jiuxin capsule;endothelium cell;VCAM-1;ICAM-1 |
| Author Name | Affiliation | | JIN Hui-min | Tianjin University of TCM, Tianjin 300193, China | | LI Pei-fen | Tianjin University of TCM, Tianjin 300193, China | | LIU Liang | Tianjin University of TCM, Tianjin 300193, China | | 范英昌 | 天津中医学院, 天津, 300193 |
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| Abstract
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| [Objective] To study the proective effect of Jiuxin capsule against hypoxia and blood endothelium injury by low density lipoprotein(LDL).[Methods] Hypoxia and blood endothelium injury were induced in cell culture in vitro. The influence of Jiuxin capsule on adhesion molecule-1(VCAM-1) and intercellular adhesion molecule-1(ICAM-1) in blood endothelium was observed with immunohistochemistry.[Results] The expression of VCAM-1 and ICAM-1 was obviously increased in the hypoxia or LDL state. The Jiuxin capsule may obviously down-regulated this expression.[Conclusion] The Jiuxin capsule may protect the endothelium cell against injury induced by hypoxia and LDL. |
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