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| Investigation on Effective Dosage of Polyglucoside of Tripterygium Wilfordii in Treating Rheumatic Arthritis |
| Hits 1654 Download times 1733 Received:June 08, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2006.01.12 |
| Key Words
polyglucoside of tripterygium wilfordii;rheumatic arthritis;the minimum effective drug dosage |
| Author Name | Affiliation | | ZHOU Yan-li | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | | LIU Wei | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | | ZHANG Lei | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To investigate the effective dosage of polyglucoside of tripterygium Wilfordii in treating rheumatic arthritis(RA)for guiding the clinical rational administration.[Methods] Five hundred and sixty-seven patients treated with this drug were selected and analyzed retrospectively.The effect was classified as improvement,advance and obviously advance.The relation between improvement and administration time and administration dosage was studied.[Result] The average between administration dosage of advance group and improvement group had obvious difference(P<0.05).However,the average administration dosage between advance group and obvious advance group had not difference(P>0.05).[Conclusion] In a certain range,the polyglucoside of tripterygium Wilfordii should be administrated with sufficient time interval and dosage in the largest effective administration limit in order to achieve the best curative effect. |
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