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| Influence of Yugong Capsule on IL-2-IFN-NKC Immunological Regulation Network in Rats with Deficiency of Kidney-Yang Syndrome and Dysplasia of Uterus |
| Hits 2042 Download times 2075 Received:July 30, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2006.01.23 |
| Key Words
Yugong Capsule;deficiency of kidney-yang;dysplasia of uterus;immunological regulation;experimental research |
| Author Name | Affiliation | | YANG Jian-bing | Shanxi College of TCM, Xianyang 712083, China | | CHEN Mei | Shanxi College of TCM, Xianyang 712083, China | | CUI Xiao-ping | Shanxi College of TCM, Xianyang 712083, China | | 王宗柱 | Shanxi College of TCM, Xianyang 712083, China |
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| Abstract
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| [Objective] To observe the influence of Yugong(invigorating the uterus)Capsule on IL2-IFN-NKC immunological regulation network in rats with deficiency of kidney-yang syndrome and dysplasia of uterus and discuss the mechanism of treating dysplasia of uterus.[Methods] Forty immature SD female mice were randomly divided into four groups:control group(A),model group(B),Yougui pills group(C),Yugong capsule(D).The deficiency kidney-yang syndrome and dysplasia of uterus in rats were established by injecting hexadecadrol and bilateral oophorectomy.The weight of thymus,spleen,uterus,the IL-2,IFN and NKC activity of the spleen were determined.[Result] The weight of thymus,spleen uterus and IL-2,IFN and NKC activity in the treatment group were obviously lower than that in the normal group in rays with deficiency of kidney-yang syndrome and dysplasia of uterus(P<0.01).Yugong Capsule could increase the weight of thymus,spleen,uterus and IL-2,IFN and NKC activity(P<0.01).[Conclusion] Nonspecific immunity decreased in rats with deficiency of kidney-yang syndrome and hypoplasia of uterus.Yugong Capsule can promote the development of uterus,enhance IL-2,IFN and NKC activity and up-regulate its immune function in rats with deficiency of kidney-yang syndrome and sysplasia of uterus.YuGong capsule possesses a regulative effect on nerve-endocrine-immune networks. |
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