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| Synergic Action of Chinese Herbs with HuoxueHuayu Effect on Cholagogic Effect of Chinese herbs with QingreLidan Effect |
| Hits 1489 Download times 2255 Received:October 26, 2005 |
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| DOI
10.11656/j.issn.1672-1519.2006.01.28 |
| Key Words
HuoxueHuayu herbs;QingreLidan herbs;Lidanling;synergistic action;rat;T-tube for external drainage of bile |
| Author Name | Affiliation | | XUE Xiao-ping | Tianjin Institute of Acute Abdomen of Integrated Traditional Chinese and Western Medicine, Tianjin 300100, China | | LI Dong-hua | Tianjin Institute of Acute Abdomen of Integrated Traditional Chinese and Western Medicine, Tianjin 300100, China | | LIU Zheng | Tianjin Institute of Acute Abdomen of Integrated Traditional Chinese and Western Medicine, Tianjin 300100, China | | 崔乃强 | Tianjin Institute of Acute Abdomen of Integrated Traditional Chinese and Western Medicine, Tianjin 300100, China |
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| Abstract
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| [Objective] To investigate the synergistic action of HuoxueHuayu(promoting blood circulation and dissolving stagnant blood)herbs on the cholagogic effect of QingreLidan medicine(clearing away heat and promoting bile secretion)herbs.[Methods] Thirty-six healthy Wistar rats were randomly divided into six groups:normal group,saline control group,HuoxueHuayu group,QingreLidan group,Lidanling(HuoxueHuayu and QingreLidan herbs together)group and Ursodeoxycholic acid group.Except for the normal group,a T-tube for external drainage of bile was inserted in all the other groups.Specimens were collected seven days after administration to determine individually bile flow rate,bile and serum bilirubin,direct bilirubin,total bile acid,cholesterol and phospholipids.[Result] Compared with other groups,both ursodeoxycholic acid group and Lidanling group may significantly promote normal rat bile flow rate,bile bilirubin,total bile acid and decreased bile cholesterol,significantly decreased serum bilirubin,serum total bile acid and serum cholesterol levels with little effect on phospholipid of bile and serum.[Conclusion] HuoxueHuayu herbs has showed synergistic action with QingreLidan herbs. |
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