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| Effect of QiZhen Decoction on Fibronectin Adhesive Ability of Human Carcinoma of Large Intestine |
| Hits 1640 Download times 1928 Received:June 12, 2006 |
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| DOI
10.11656/j.issn.1672-1519.2006.04.22 |
| Key Words
strengthening the body resistance,detoxication and activating blood circulation;QiZhen decoction;L-10 cell with high metastasis rate of human rectal carcinoma;fibronectin |
| Author Name | Affiliation | | MENG Jing-yan | Tianjin University of TCM, Tianjin 300193, China | | YING Sen-lin | Tianjin University of TCM, Tianjin 300193, China | | LI Yan | Tianjin University of TCM, Tianjin 300193, China | | 阚湘苓 | Tianjin University of TCM, Tianjin 300193, China | | 胡永军 | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To explore the effect of QiZhen decoction,having effect of strengthening the body resistance and detoxication and activating blood circulation on the adhesive ability of fibronectin in L-10,a carcinoma cell with high-metastasis rate of large intestine.[Methods] The resisting effect of QiZhen decoction on the adhesive ability of fibronectin of L-10 was measured with cell culture method in vitro.[Results] QiZhen decoction could markedly inhibit the adhesive ability of fibronectin in L-10 cell dose-dependently.This resistance changed with time.It achieved at the peak level at 120 minutes later,then reduced gradually.[Conclusions] QiZhen decoction possesses a function to resist the adhesion of fibrinectin of L-10 cell obviously.So QiZhen decoction can inhibit the infiltration and metastasis of carcinoma. |
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