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| Effect of the Huishen Granule on Morphology of Nerve and Skeletal Muscle Tissues After Sciatic Nerve Injury in Rats |
| Hits 1696 Download times 2145 Received:March 22, 2006 |
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| DOI
10.11656/j.issn.1672-1519.2006.04.27 |
| Key Words
Hui-shen granule;sciatic nerve;peripheral nerve;regeneration;morphology |
| Author Name | Affiliation | | ZHAO Ting-hao | Tianjin University of TCM, Tianjin 300193 China | | BIAN Jing-zhi | The TCM Hospital of Wuqing District, Tianjin 301700, China | | CHEN Hui-wa | The TCM Hospital of Wuqing District, Tianjin 301700, China | | 陈洪浩 | The TCM Hospital of Wuqing District, Tianjin 301700, China | | 陈宝贵 | The TCM Hospital of Wuqing District, Tianjin 301700, China | | 郭义 | Tianjin University of TCM, Tianjin 300193 China |
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| Abstract
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| [Objective] To investigate the effect of Hui-shen(restoring mental function)granule on the morphologic change of nerve tissues and the shape metrology of the calf muscular cells during the regeneration to indicate the therapeutic effect.[Methods] The nerve injury was induced by clamping the left sciatic nerves of Wistar rats.The model rats were administered once a day for 14 days with Hui-shen granula.Finally the nerve tissues was stained with HE and Silver dyeing.We also observed the ultrastructures of nerve tissues.The muscle tissues were stained with HE and the muscle section area of gastroceminus were analyzed.[Results] The Hui-shen granule could significantly accelerate the recovery of nerve and muscle tissues.There was significant difference between the model group and the Hui-shen granule group on the muscle section area of gastroceminus.[Conclusions] The Hui-shen granule is an effective Chinese medicine herb. |
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