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Effect of Decoction of Branch of Juglans Maxim on Subpopulation of T-lymphocyte in Peripheral Blood of Tumor-loaded Mice
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DOI   10.11656/j.issn.1672-1519.2006.05.21
Key Words   The decoction of Juglans Maxim’s branch (DJM);S180 sarcoma;Th1/Th2;IL-2;IL-4
Author NameAffiliation
YU Xiao-hong  
HU Yan-wen  
YU Yang  
赵春卉  
Abstract
    [Objective] To study the regulative effects of decoction of the Branch of Juglans Maxim(DJM) on immunity and the possible mechanism of anti-tumor in tumor-loaded mice with S180 tumor cells.[Methods] The influence of DJM on IL-2,IL-4 and the regulative action of DJM on the CD4+T cells and CD8+T cells in mice bearing S180 tumor cells were observed.[Results] The level of IL-2 increased(P<0.05) by DJM,but the level of IL-4(P<0.05)decreased. The expression of the CD4+T cells increased(P<0.05) and the expression of the CD8+T cells decreased(P<0.05).[Conclusions] The anti-tumor mechanism of DJM may contribute to the regulative effect on abnormal immunological condition in tumor-loaded mice with S180 tumor cells.

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