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| Activating Effect of Dandelion on Sexual Hormone in Hypothalamus and Hypophysis |
| Hits 1662 Download times 2603 Received:August 11, 2006 |
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| DOI
10.11656/j.issn.1672-1519.2006.06.30 |
| Key Words
dandelion;hypothalamus;hypophysis;sexual hormone |
| Author Name | Affiliation | | SHAO Hui | Kobe Medical College of Japan, Kobe, Japan | | KOBA Rika | Kobe Medical College of Japan, Kobe, Japan | | HAYAKAWO Hinkou | Kobe Medical College of Japan, Kobe, Japan | | 工藤卓 | 工藤诊所, 日本 | | 高秀梅 | 天津中医药大学, 天津, 300193 | | 宋金波 | 天津中医药大学, 天津, 300193 | | 柳源延章 | 产业医科大学, 日本 |
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| Abstract
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| Dandelion was widely used in gynecology and obstetrics in China and Germany,especially in the clinical treatment of hypoovarianism,infertility and menopausal syndrome etc.In modern medicine,it was proposed that the medicine could afford some intervention with the endocrinologic mechanism in hypothalamus,hypophysis and sexual gland axle.The aim of this experiment is to explore the changes of various kinds of hormones in the women in child-bearing period before and three months after treament,to explore the mechanism from the endocrinology principle and verify the effect of T-1,the main extracted component of dandelion,on ovulation and central system from the viewpoint of LH-RH secretion.These results showed that FSH,LH,E2 and P had an increased tendency,while PRL was decreased.The self-feeling symptoms of dysmenorrhea and limbs chilly were obviously improved.T-1 could accelerate ovulation,increase LH-RH content of hypothalamus and hypophysis in excperiment.It was considered that the site of effect was hypothalami and hypophysis system.T-1 could further increase the lever of nerve conduction transmitter,such as NE,DA and SR.These substances might closely correlated to the attack of dementia.The pharmacological effects were worthy of deeply investigation in the future. |
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