[Objective] To investigate the effect of Shenmai (Ginseng and Ophiopogon japonicus) injection (SI) on heart function in patients with congestive heart failure (CHF).[Methods] Patients were randomly divided into group A (treated with routine medicine therapy with SI 40 mL in 250 mL+5% Glucose infused intravenously) and group B(treated with routine medicine therapy).Left ventricular end-systolic volume (LVESV),left ventricular end-diastolic volume (LVEDV),left ventricular ejection fraction (LVEF) were measured using Color Doppler echocardiogram before and after treatment.[Results] Group A was obviously better than group B in improving heart function(P<0.01).LVESV,LVEF of group A and group B were improved after treatment compared with before (P<0.01).The effect of group A was obviously better than that of group B (P<0.05).[Conclusions] SI can improve the heart function in patients with CHF,and can be an important medicine in treating CHF.
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