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Influence of Yiniaoling on immune organ in rats with insufficiency of kidney-yang
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DOI   10.11656/j.issn.1672-1519.2007.01.28
Key Words   Yiniaoling;insufficiency of kidney-yang;immune organ;influence
Author NameAffiliation
ZHANG Zhu  
MA Ji-wei  
Abstract
    [Objective] To explore the influence of Yiniaoling (treating overflow incontinence) on the immune organ in rats with insufficiency of kidney-yang.[Methods] The rats were randomly divided into the normal control group,the insufficiency of kidney-yang model group,the insufficiency of kidney-yang and Jingui Shenqi Pill group,the insufficiency of kidney-yang and large dose of Yiniao Ling group and the insufficiency of kidney-yang and small dose of Yiniaoling group.The physiological saline (0.3mL) was injected into lower limb intravenously in the normal group,cortisone acetate (25mg/g) was injected into lower limb intramuscularly in other groups continually for 8 weeks.After that,the body weight was measured and the rats were killed.The spleen,thymus and adrenal gland were removed rapidly and weighted.The spleen index and the thymus index were calculated.The spleen and thymus were examined with microscopy.[Results] The spleen index and thymus index were reduced in model group with very marked difference when compared with the normal group (P<0.01).The spleen index and thymus index had extremely significant difference when compared large dose of Yiniaoling group with the model group (P<0.01); the thymus index had extremely significant difference when compared small dose of Yiniaoling group with the model group (P<0.01); the spleen index had significant difference when compared small dose of Yiniaoling group with the model group (P<0.05).[Conclusions] The effect of Yiniaoling in treating stress incontinence of patient with yang deficiency of kidney maybe performed by increasing of the immunologic activity.

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