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| Effect of Maqin Kechuan mistura on eosinophil and its cationic protein in guinea pigs with asthma |
| Hits 1663 Download times 1793 Received:December 11, 2006 |
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| DOI
10.11656/j.issn.1672-1519.2007.02.05 |
| Key Words
Asthma;Maqin Kechuan mistura;EOS;ECP |
| Author Name | Affiliation | | MA Zuo-ying1 | Tianjin University of TCM, Tianjin 300193, China | | SUN Zeng-tao2 | The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300193, China | | HE Shan | Tianjin TEDA Hospital, Tianjin 300475, China | | 刘恩顺 | The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To observe the effect of Maqin Kechuan mistura (Mistura of Ephedra and Baikal Skullcap Root for Treating Asthma) on eosinophil (EOS) and eosinophil cation protein (ECP) of guinea pigs with asthma. The mechanism of Maqin Kechuan mistura was explored. [Methods] Sixty male Hartley guinea pigs were divided into four groups randomly: control group, Asthma group, Prednisone group and Maqin Kechuan mistura group. The amount of EOS in the lung was calculated under optical microscope and the concentration of ECP in serum was examined by radioimmunoassay method. [Results] The amount of EOS in Maqin Kechuan mistura group was reduced significantly. The content of ECP in serum of guinea pigs of Maqin Kechuan mistura group was also remarkably different from that of asthma group. [Conclusions] Maqin Kechuan mistura may reduce the amount of EOS and the content of ECP of guinea pigs with asthma. |
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