|
| Therapeutic effect of Oxymatrine combined with Laminudine in treating patients with chronic hepatits B |
| Hits 1803 Download times 2163 Received:October 06, 2006 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2007.02.09 |
| Key Words
Oxymatrine;Laminudine;Chronic hepatitis B;therapy;YMDD mutation |
| Author Name | Affiliation | | LI Jia1 | Military Medical Postgraduate Institute, General Hospital of PLA, Beijing 100853, China | | LIANG Shu-ren | Tianjin Hospital of Infectious Disease, Tianjin 300192, China |
|
| Abstract
|
| [Objective] To investigate the effect of Oxymatrine combined with Lamivudine on patients with chronic hepatitis B. [Methods] Seventy-five patients were divided into two groups. The patients in therapy group were accepted Oxymatrine combined with Laminudine, and the patients in control group Lamivudine alone. The course of treatment was twelve months. [Results] The negative-conversion rates of HBeAg were higher, and the rate of YMDD mutation was lower in therapy group than that in control group(P<0.05). [Conclusions] The treatment of Oxymatrine combined with Laminudine can markedly improve the antiviral effect and reduce the resistance to Lamivudine. |
|
