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| Effect of LiDanLing on bile acid in drained bile in patients with pigment gallstone |
| Hits 1470 Download times 1990 Received:November 20, 2006 |
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| DOI
10.11656/j.issn.1672-1519.2007.02.10 |
| Key Words
LiDanLing medicine;pigment gallstone;bile components |
| Author Name | Affiliation | | WANG Qian | Tianjin Nankai Hospital, Tianjin 300100, China | | SUN Bai-jun | Tianjin Nankai Hospital, Tianjin 300100, China | | LI Dong-hua | Tianjin Nankai Hospital, Tianjin 300100, China | | 崔乃强 | Tianjin Nankai Hospital, Tianjin 300100, China |
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| Abstract
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| [Objective] To study the effects of LiDanLing(chloretic herb) medicine on the compositions of bile acid in drained bile in patients with pigment gallstone. [Methods] Twenty-seven patients suffered from primary pigment stones with choledochostomy, T tube drainage or ENBD were selected. After operation the patient was treated with LiDanLing medicine orally, and the drained bile was collected before and on the 1, 3, 5, 7th day after treatment to detect TBA and GCA, TCA, GCDCA by HPLC. [Results] Bile TBA, GCA, TCA and GCDCA gradually increased after treatment with ursodeoxycholic acid tablets and LiDanLing medicine plus ursodeoxycholic acid tablets (P<0.05). The increasing extent of TCM only group had no obvious change when compared with control group(P>0.05). [Conclusions] Bile TBA and GCA, TCA, GCDCA are gradually increased during treatment with LiDanLing medicine plus ursodeoxycholic acid tablets, so LiDanLing medicine can prevent pigment gallstone. |
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