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Effect of astragalus polysaccharide on suppression of bone marrow after chemotherapy in patients with malignant tumor
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DOI   10.11656/j.issn.1672-1519.2007.02.12
Key Words   astragalus polysaccharide;malignant tumor;chemotherapy side effect;suppression of bone marrow
Author NameAffiliation
ZHAO Mei-rong Tianjin University of TCM, Tianjin 300193, China 
ZHOU Jie The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300150, China 
Abstract
    [Objective] To explore the effect of astragalus polysaccharide on the suppression of bone marrow after chemotherapy in patients with malignant tumor. [Methods] Eighty patients were randomly divided into treatment group and control group. The patients in treatment group (26 cases) were infused with astragalus polysaccharide intravenously, 250 mg daily from days 1 to 7 before chemotherapy, while the control group was treated with routine chemotherapy only. Then, the laboratory tests were performed after treatment and compared the change of white blood cell count, neutrophil count and platelet count at the 4, 7, 10 and 14 day. [Results] The curative effect in treatment group was superior to that in control group. There was notable difference between two groups at the 10, 14 day(white blood cell count and neutrophil count) and at the 14 day (platelet count). [Conclusions] Astragalus polysaccharide can significantly ameliorate the suppression of bone marrow after chemotherapy and improve the life quality of patients.

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