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| Research on the External Signs and Hemorheology in Rats with Qi deficiency and blood stasis |
| Hits 1550 Download times 1655 Received:January 11, 2007 |
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| DOI
10.11656/j.issn.1672-1519.2007.02.24 |
| Key Words
Qi deficiency and blood stasis, rat model;external signs;dark purple tongue;hemorrheology |
| Author Name | Affiliation | | HU Xin-gang | The Dong Fang Hospital of Beijing University of TCM, Beijing 100078, China | | ZHANG Yun-ling | The Dong Fang Hospital of Beijing University of TCM, Beijing 100078, China | | LIU Hong-sheng | The Dong Fang Hospital of Beijing University of TCM, Beijing 100078, China | | 娄金丽 | The Dong Fang Hospital of Beijing University of TCM, Beijing 100078, China | | 郑宏 | The Dong Fang Hospital of Beijing University of TCM, Beijing 100078, China | | 张锦 | The Dong Fang Hospital of Beijing University of TCM, Beijing 100078, China | | 闫妍 | The Dong Fang Hospital of Beijing University of TCM, Beijing 100078, China | | 黄启福 | Beijing University of TCM, Beijing 100029, China |
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| Abstract
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| [Objective] To establish a model of Qi deficiency and blood stasis model in rats and discover the sensitive external signs and the hemorheologic property. [Methods] Qi deficiency and blood stasis was induced by exhausting swim every day for a certain period (1, 2 or 4 w). External signs and hemorheology were observed. [Results] Compared with normal rats, average body weight of model rats (2 and 4 w) was less, time of swimming (2 and 4 w) was shorter, while time of staying in the middle square in open-field analyses (2 and 4 w) was longer. In model rats (1, 2 and 4 w) the tongue color turned from light red to dark or dark purple. Blood viscosity increased (2 w), PT (1, 2 and 4 w), APTT (4 w) and FIB (4 w) decreased in model. [Conclusions] Qi deficiency and blood stasis is successfully induced in rats based on the evidence of relative external signs and hemorheological property as above. |
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