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| Effect of Perilla Frutescens Stem on contractile activity of isolated colon smooth muscle strips in rats |
| Hits 1713 Download times 2122 Received:November 30, 2006 |
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| DOI
10.11656/j.issn.1672-1519.2007.02.26 |
| Key Words
Perilla frutescens stem;gastrointestinal motility;contractile activity;colon |
| Author Name | Affiliation | | LIU Rong | General Hospital of Tianjin Medical University, Tianjin 300052, China | | TANG Fang | General Hospital of Tianjin Medical University, Tianjin 300052, China |
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| Abstract
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| [Objective] To study the effect of Perilla frutescens stem on the contractile activity of isolated colon smooth muscle strips in rats. [Methods] Functional dyspepsia(FD) model was induced in lower limb in ischemia and reperfusion rats(LIR). The circular muscle strips of rat colon were suspended in a thermostat pool for perfusion. The average contractile amplitude and the resting tension of colonic muscle strips were recorded. [Results] Perilla frutescens stem could increase the average contractile amplitude of colonic muscle strips in FD rats and decrease the resting tension. But it was no use for normal rats. [Conclusions] The results indicate that Perilla frutescens stem has significant exciting action on contractile activity of isolated colonic smooth muscle strips in FD model rats. |
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