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| Study on the inclusion complex of borneol with hydroxypropyl-β-cyclodextrin |
| Hits 1714 Download times 2151 Received:October 20, 2006 |
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| DOI
10.11656/j.issn.1672-1519.2007.02.30 |
| Key Words
borneol;hydroxypropyl-β-cyclodextrin;inclusion complex phase solubility diagram, X-ray diffraction |
| Author Name | Affiliation | | WANG Jing1 | Tianjin University of TCM, Tianjin 300190, China | | ZHANH Tie-jun2 | Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China | | LIAO Mao-liang | Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China | | 徐晓宏 | Tianjin University of TCM, Tianjin 300190, China |
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| Abstract
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| [Objective] To study the preparation technology of the inclusion complex of the borneol-hydroxypropyl-β-cyclodextrin and identify the formation of inclusion complex. [Methods] The inclusion complex was prepared by freeze-drying technique. Its structure was proved by TLC, phase solubility diagram, X-ray diffraction, NMR, SEM. [Results] The results indicated that the inclusion complex of the borneol- hydroxypropyl-β-cyclodextrin was formed. [Conclusions] Hydroxypropyl-β-cyclodextrin is available to include the borneol. The solubility of borneol is increased in aqueous solution. |
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