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| Correlation between changes of endotoxin, inflammatory mediators and intestinal endotoxemia in patients with excess syndrome of Yang Ming Fu-organ |
| Hits 1898 Download times 1932 Received:February 01, 2007 |
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| DOI
10.11656/j.issn.1672-1519.2007.03.06 |
| Key Words
excess syndrome of Yang Ming Fu-organ;intestinal endotoxemia;TNF-α;IL-6;IL-10 |
| Author Name | Affiliation | | ZHANG Xi-po | Tianjin Medical University, Tianjin 300052, China | | CUI Nai-qiang | Tianjin Nankai Hospital, Tianjin 300100, China | | YUAN Hong-xia | Tianjin University of TCM, Tianjin 300193, China | | 张国骏 | Tianjin University of TCM, Tianjin 300193, China | | 于强 | Tianjin Nankai Hospital, Tianjin 300100, China |
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| Abstract
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| [Objective] To observe the change of endotoxin, inflammatory mediators in the patients with excess syndrome of Yang Ming Fu-organ and explore the correlation between the change of endotoxin, inflammatory mediators and Intestinal endotoxemia. [Methods] The patients with excess syndrome of Yang Ming Fu-organ were randomly divided into two group: conventional therapy control group and traditional Chinese medicine treatment group. The change of ET, TNF-α, IL-6 and IL-10 before and after treatment was determined. [Results] The level of ET, TNF-α, IL-6 and IL-10 was decreased after treatment in the patients with excess syndrome of Yang Ming Fu-organ. Especially, the change of ET, TNF-α, IL-6 and IL-10 change in treatment group was more obvious than that in control group(P<0.05). [Conclusions] Compound Dachengqi decoction may regulate the level of ET, TNF-α, IL-6 and IL-10 in patients with excess syndrome of Yang Ming Fu-organ. There are some correlations between the change of ET, TNF-α, IL-6 and IL-10 and Intestinal endotoxemia. |
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