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| Systemic evaluation of Compound Preparation of Salvia Miltiorrhiza in treating stable angina in a randomized controlled trial |
| Hits 1662 Download times 2011 Received:March 06, 2007 |
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| DOI
10.11656/j.issn.1672-1519.2007.03.09 |
| Key Words
Compound Preparation of Salvia Miltiorrhiza;angina;systematic evaluation |
| Author Name | Affiliation | | ZHANG Jun-hua | Tianjin University of TCM, Tianjin 300193, China | | SHANG Hong-cai | Tianjin University of TCM, Tianjin 300193, China | | GAO Xiu-mei | Tianjin University of TCM, Tianjin 300193, China | | 王辉 | Tianjin University of TCM, Tianjin 300193, China | | 项耀祖 | Tianjin University of TCM, Tianjin 300193, China | | 曹红波 | Tianjin University of TCM, Tianjin 300193, China | | 任明 | Tianjin University of TCM, Tianjin 300193, China | | 戴国华 | Tianjin University of TCM, Tianjin 300193, China | | 毛静远 | 天津中医药大学第一附属医院, 天津, 300193 | | 张伯礼 | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To evaluate the curative effect and safety of Compound Preparation of Salvia Miltiorrhiza in treating stable angina in a randomized controlled trial. [Methods] From Cochrane Centre, MEDLINE, EMBASE, CBM, CNKI and VIP database the corresponding materials of Compound Preparation of Salvia Miltiorrhiza in treating stable angina in a randomized controlled trial were collected. Quality evaluation was done referring to the standard of Cochrane handbook 4.26. [Results] Thirty-three literatures were selected altogether. The symptomatic improvement of angia was adopted as the evaluation index in thirty-two researches and its RR(random) value and 95% CI were 1.16(1.10, 1.23). The improvement in ECG was adopted as evaluation index in thirty researches and its RR(random) value and 95% CI were 1.38(1.25, 1.51). The adverse reaction induced by Compound Salvia Miltiorrhiza Preparation was light stomach discomfort. Its incidence rate was 3.4% and 95% CI 2.5%, 4.5%. [Conclusions] According to the systematic evaluation result and comparing to nitrate medicine, it is considered that the Compound Preparation of Salvia Miltiorrhiza has some superiority in improving angina symptoms and myocardial ischemia. |
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