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| Effect of cornel total glycoside on bone metabolism and bone density in caponized rats |
| Hits 2064 Download times 2201 Received:January 16, 2007 |
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| DOI
10.11656/j.issn.1672-1519.2007.04.29 |
| Key Words
cornel total glycoside;osteoporosis;bone metabolism;bone density |
| Author Name | Affiliation | | LI Ping | Tianjin Nankai Hospital, Tianjin 300100, China | | LI Jing | Tianjin University of TCM, Tianjin 300193, China | | WANG Hui-ming | Tianjin Hospital of TCM, Tianjin 300140, China |
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| Abstract
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| [Objective] To explore the mechanism of cornel total glycoside,the main effective component in Yishen Yanggan for oral use,in treating osteoporosis. [Methods] Wistar rats were randomly divided into five groups: sham operated group,model group,the high,middle and low dosage of cornel total glycoside group. Ca,P,E2 were determined and bone density experiment was carried out. [Results] The E2 content and bone density of cornel total glycoside group were obviously higher than that of model group. The blood Ca and P of cornel total glycoside group had not obvious difference when compared with that of model group. [Conclusions] The cornel total glycoside has bitter regulative effect on bone metabolism and bone density of caponized rats. |
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