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Influence of Baoyuan Huoxue Granule on CD11b/CD18 and bcl-2/bax expression in aged patients with deficiency of Qi and kidney
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DOI   10.11656/j.issn.1672-1519.2007.05.06
Key Words   Baoyuan Huoxue Granule;deficiency of Qi and kidney;aged;CD11b/CD18;bcl-2/bax
Author NameAffiliation
HU Jian Department of TCM, General Hospital of PLA, Beijing 100853, China 
YANG Ming-hui Department of TCM, General Hospital of PLA, Beijing 100853, China 
LU Jun-zhang Department of TCM, General Hospital of PLA, Beijing 100853, China 
丛玉隆 解放军总医院临床检验科, 北京, 100853 
邓新立 解放军总医院临床检验科, 北京, 100853 
Abstract
    [Objective] To study the clinic influence of Baoyuan Huoxue(protecting vital QI and activating blood circulation) Granule in aged patients with deficiency of Qi and kidney by determining the level of CD11b/CD18 and bcl-2/bax.[Methods] Sixty such aged patients were randomly divided into two groups. Thirty patients in treatment group were treated with Baoyuanhuoxue granule and another 30 in control group received no treatment. The expression of CD11b/CD18 and bcl-2/bax before and after treatment in both groups was observed and analyzed.[Results] Baoyuan Huoxue Granule could reduce the level of CD11b/CD18(P<0.01),elevate the level of bcl-2/bax in the aged patients with deficiency of Qi and kidney (P<0.01).[Conclusions] Baoyuan Huoxue Granule may regulate the function of CD11b/CD18 and bcl-2/bax. This may probably one of the effect mechanism in treating aged patients with deficiency of Qi and kidney.

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