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| Effect of baicalin on migration of nerves precursor cell by interfering with hypoxia in astrocyte |
| Hits 1768 Download times 1806 Received:March 12, 2007 |
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| DOI
10.11656/j.issn.1672-1519.2007.05.38 |
| Key Words
nerves precursor cell;migration;astrocyte;hypoxia;baicalin;VEGF;MCP-1 |
| Author Name | Affiliation | | Yisidatoulawo | Japan | | XU Qiang | Tianjin University of TCM, Tianjin 300193, China | | JIANG Xi-juan | Tianjin University of TCM, Tianjin 300193, China | | 王少峡 | Tianjin University of TCM, Tianjin 300193, China | | 赵亚莉 | Tianjin University of TCM, Tianjin 300193, China | | 张艳军 | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To explore the relation between the neuroprotective effect of baicalin and endogenous nerves precursor cell(NPC). [Methods] Taking the two-side cerebral cortex in Wistar rats as the sample to cultivate astrocyte and determine the mRNA expression of chemotatic factor with PCR.[Results] The hypoxia astrocyte treated with baicalin may promote the migration of NPC.[Conclusions] The baicalin has a certain neuroprotective effect and has provided some experimental basis for its clinical application. |
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