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Clinical trial of comprehensive therapeutic protocal in multicenter on acute ischemic stroke treated with traditional Chinese medicine
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DOI   10.11656/j.issn.1672-1519.2007.06.07
Key Words   acute ischemic stroke;multi-center clinical trial;NIHSS
Author NameAffiliation
PAN Feng  
GUO Jian-wen  
WANG Xin-zhi  
杨友松  
裴建  
谭吉林  
顾卫  
李伟峰  
黄燕  
Abstract
    [Objective] To observe the effect of a comprehensive protocol of integrated Chinese and western medicine(ICWM) in treating acute ischemic stroke.[Methods] A multi-center, prospective, random assigned and controlled clinical trial was adopted in 606 patients of acute ischemic stroke. They were divided into the treatment group(274 cases) treated with ICWM protocol, and the control group(263 cases) treated with western medicine plus placebo, and BI, mRS were assessed after treatment.[Results] Compared with the control group, 21 days later the assessment showed that the neurological impairment (national institute of health stroke scale, NIHSS) rate was lower(P<0.05), and the symptoms and signs levels (Stroke Scale of Traditional Chinese Medicine, SSTCM) were improved (P<0.05)in the treatment group and those were not observed in the control group.[Conclusions] The ICWM treatment protocol used in this study may improve neural function and symptoms and signs of acute ischemic stroke patients.

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