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| Determination of salvianolic acid B in Qingxin Tablet by HPLC |
| Hits 1294 Download times 1435 Received:September 20, 2007 |
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| DOI
10.11656/j.issn.1672-1519.2008.01.31 |
| Key Words
Qingxin Tablet;Salvianolic acid B;HPLC |
| Author Name | Affiliation | | CHENG Peng | Department of Pharmacy, Affiliated Hospital of Bengbu Medical College, Bengbu 233004, Anhui Province, China | | PAN Qin | Research & Development Center, Tianjin Zhongxin Pharmaceutical Group, Co.Ltd, Tianjin 300457, China | | XU Shan-chu | Department of Pharmacy, Affiliated Hospital of Bengbu Medical College, Bengbu 233004, Anhui Province, China |
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| Abstract
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| [Objective] To establish the determining method of the content of salvianolic acid B in Qingxin Tablet. [Methods] HPLC analysis was performed on a YMC-pack C18 column (150 mm×4.6 mm, 5 μm) with methanol-acetonitrile-formic acid-water (30:10:1:59) as mobile phase; the detection wavelength was 286 nm and the column temperature was 25 ℃. [Results] The standard curves of salvianolic acid B showed a good linearity and the average recovery weas 99.62% with RSD 1.46% (n=8). [Conclusions] The method can be used for the content determination of salvianolic acid B in Qingxin Tablet. |
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