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Clinical effect of cinobufacini injection in treating advanced malignant tumor of digestive tract in 30 patienmts
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DOI   10.11656/j.issn.1672-1519.2008.02.07
Key Words   Cinobufacini;digestive tract;malignant tumor;Therapy
Author NameAffiliation
NIU Jing-xiu Department of Integrated Traditional Chinese and Western Medicine, Cancer Hospital of Tianjin Medical University, Tianjin 300060, China 
XIE Guang-ru Department of Integrated Traditional Chinese and Western Medicine, Cancer Hospital of Tianjin Medical University, Tianjin 300060, China 
LIU Dong-ying Department of Integrated Traditional Chinese and Western Medicine, Cancer Hospital of Tianjin Medical University, Tianjin 300060, China 
Abstract
    [Objective] To observe the clinical effect of Cinobufacini injection on treating advanced malignant tumor of digestive tract.[Methods] Sixty patients with advanced malignant tumor of digestive tract were randomly divided into cino-treated group(30 patients) and control group(30 patients) according to whether receiving cinobufacini injection.The patients in the cino-treated group were treated with cinobufacini injection for one course of treatment without other anticancer therapies except supportive treatment when needed.The patients in the control group were treated only with supportive treatment.The tumor size,physical strength,cancer pain,adverse effect were observed.[Results] The clinic beneficial rate of cino-treated group(30.00%) was higher than that of the control group(23.33%) but without statistical significance.The physical strength condition of cino-treated group(70.00%) was better than that of the control group(43.33%)with statistical significance.The relieving cancer pain of cino-treated group(77.27%) was better than that of the control group(25.00%)with statistical significance.[Conclusions] Cinobufacini injection can inhibit the proliferation of cancer,improve physical strength and relieve cancer pain.It has curative effect in pilliative therapy of advanced malignant tumor of digestive tract.

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