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Effects of Xinfeng capsule on patients of active rheumatoid arthritis with depression |
Hits 1442 Download times 1571 Received:June 18, 2008 |
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DOI
10.11656/j.issn.1672-1519.2008.04.04 |
Key Words
rheumatoid arthritis;depressive;Xinfeng capsule;quality of life |
Author Name | Affiliation | LIU Jian | Department of Rheumatology, the First Affiliated Hospital to Anhui College of TCM, Hefei 230013, China | YU Xue-fang | Department of Rheumatology, the First Affiliated Hospital to Anhui College of TCM, Hefei 230013, China | ZONG Rui-kai | Department of Rheumatology, the First Affiliated Hospital to Anhui College of TCM, Hefei 230013, China | 汪元 | Department of Rheumatology, the First Affiliated Hospital to Anhui College of TCM, Hefei 230013, China |
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Abstract
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[Objective] To observe the effects of Xinfeng capsule (XFC) on patients of active rheumatoid arthritis(RA) with depression and study its mechanism. [Methods] Forty RA patients were randomly divided into two groups. The patients of treatment group were treated with XFC, and those of control group with Fengshigutong capsule. The main symptoms and signs, integral calculus of quality of life, self-rating depression scale(SDS) and laboratory results etc. were observed. [Results] The effects of XFC group were similar to that of Fengshigutong capsule in improving symptoms and signs, active index etc. But the effect of XFC was higher than Fengshigutong capsule in improving SDS standard score, the symptoms of insufficiency of spleen, integral calculus of quality of life and serum iron. [Conclusion] XFC capsule can improve RA patient’s depressive emotion and life quality. Its mechanism is probably related with its integrated regulation in increasing organism immune function, improving quality of life and anemia symptoms in RA patients. |
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