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Effects of Xinfeng capsule on patients of active rheumatoid arthritis with depression
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DOI   10.11656/j.issn.1672-1519.2008.04.04
Key Words   rheumatoid arthritis;depressive;Xinfeng capsule;quality of life
Author NameAffiliation
LIU Jian Department of Rheumatology, the First Affiliated Hospital to Anhui College of TCM, Hefei 230013, China 
YU Xue-fang Department of Rheumatology, the First Affiliated Hospital to Anhui College of TCM, Hefei 230013, China 
ZONG Rui-kai Department of Rheumatology, the First Affiliated Hospital to Anhui College of TCM, Hefei 230013, China 
汪元 Department of Rheumatology, the First Affiliated Hospital to Anhui College of TCM, Hefei 230013, China 
Abstract
    [Objective] To observe the effects of Xinfeng capsule (XFC) on patients of active rheumatoid arthritis(RA) with depression and study its mechanism. [Methods] Forty RA patients were randomly divided into two groups. The patients of treatment group were treated with XFC, and those of control group with Fengshigutong capsule. The main symptoms and signs, integral calculus of quality of life, self-rating depression scale(SDS) and laboratory results etc. were observed. [Results] The effects of XFC group were similar to that of Fengshigutong capsule in improving symptoms and signs, active index etc. But the effect of XFC was higher than Fengshigutong capsule in improving SDS standard score, the symptoms of insufficiency of spleen, integral calculus of quality of life and serum iron. [Conclusion] XFC capsule can improve RA patient’s depressive emotion and life quality. Its mechanism is probably related with its integrated regulation in increasing organism immune function, improving quality of life and anemia symptoms in RA patients.

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