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Objective basis of treating stroke before onset according to micro-lesion of brain
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DOI   10.11656/j.issn.1672-1519.2008.04.12
Key Words   micro-lesion of brain;risk factors of stroke;stroke symptoms, stroke prevention
Author NameAffiliation
QU Hong Shanghai Hospital of Integrated Traditional and Western Medicine, Neurointernal Medicine Department, Shanghai 200082, China 
Katsuya Nishimaru The Medical Science Department of Japan Fukuoka University, Neurointernal Medical Department, Fukuoka 814-0180, Japan 
Abstract
    [Objective] To explore the relation between micro-lesion of brain and stroke morbidity and risk factors, and to prove its role as an early warning sign for stroke. [Methods] Micro-lesions of brain were identified by brain MR imaging, separated by their pathological types or anatomical localizations, and their relationships with stroke symptoms and different stroke risk factors were then investigated separately. [Results] Micro-lesion of brain was mainly distributed in the upper part of the basal ganglia, and the type Ⅲ (73.3%) in anterior perforated substance and type Ⅲ (47.4%) in the upper part of the basal ganglia were most frequently observed. The upper part of the basal ganglia type Ⅲ had a close correlation with age; typeⅡ had a correlation with age and vertigo; type I had a correlation with drinking. The upper part of the basal ganglia mircro-lesions, particularly the type Ⅱand type Ⅲ had great relevance with incidence of stroke. [Conclusion] Micro-lesion of brain share common risk factors with stroke, and was also strongly correlated with the onset of stroke. Our study was the first to provide evidences for the characteristic role of mricro-lesion as a warning sign for stroke.

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