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| Influence of rubbing abdomen on regional encephalic activation in rabbits with irritable bowel syndrome |
| Hits 1613 Download times 2313 Received:April 25, 2008 |
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| DOI
10.11656/j.issn.1672-1519.2008.05.11 |
| Key Words
irritable bowel syndrome;Rubbing abdomen;fMRI |
| Author Name | Affiliation | | WANG Jin-gui | The First Hospital Affiliated to Tianjin University of TCM, Tianjin 100193, China | | WANG Yan-guo | The First Hospital Affiliated to Tianjin University of TCM, Tianjin 100193, China | | LUO Xiong-fei | The First Hospital Affiliated to Tianjin University of TCM, Tianjin 100193, China | | 孙庆 | The First Hospital Affiliated to Tianjin University of TCM, Tianjin 100193, China | | 卢燚 | The First Hospital Affiliated to Tianjin University of TCM, Tianjin 100193, China |
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| Abstract
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| [Objective] To investigate the fMRI characteristic and clinical effects of Rubbing abdomen on regional encephalic activation in rabbits with constipation-predominant irritable bowel syndrome (C-IBS). [Methods] New Zealand male albino rabbits were randomly divided into normal group, model group and Rubbing abdomen group. C-IBS was induced in all rabbits by the combined ice water intragastric administration and ice compress constraint. Encephalic regions of fMRI were observed before and after the first massage and 20 times treatment later. [Results] The activated regions were thalamencephal, Anterior Cingulate Cortex (ACC) and insula cortex (IC) in normal group, and were thalamencephal, ACC, insula cortex, brain stem, cerebellum in model group. Activated regions were thalamencephal, ACC, IC and brain stem after the first massage in Rubbing abdomen group, however the activated regions were the former three areas after 20 times. The activated encephalic intensity and range in Rubbing abdomen group were significantly lower than that in model group (P<0.01). [Conclusion] Rubbing abdomen can effectively regulate sensitization center of viscera in rabbits with C-IBS. |
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