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Study on anti-inflammatory effects of kusnezoff monkshood leaf extracts
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DOI   10.11656/j.issn.1672-1519.2009.01.34
Key Words   kusnezoff monkshood leaf;extraction;pharmacologic action;anti-inflammatory effects
Author NameAffiliation
LIU Zhan-biao Research Institute of Traditional Chinese Medicine, Tianjin University of TCM, Tianjin 300193, China 
WU Li Ji-tegusi Inner Mongolia TraditionalChinese and Mongolian Medicine Hospital, Huhhot 010020, China 
WANG Huai-song Pharmacy Faculty of Tianjin University, Tianjin 300072, China 
丁月旭 Pharmacy Faculty of Tianjin University, Tianjin 300072, China 
苏艳芳 Pharmacy Faculty of Tianjin University, Tianjin 300072, China 
Abstract
    [Objective] To explore the anti-nflammatory effects of usnezoff monkshood leaf.[Methods] Kusnezoff monkshood leaf wasextracted with chloroform and n-butanol respectively after it was prepared into extract with alcohol.The anti-inflammatory effects of kusnezoff monkshood leaf extracted with chloroform and n-butanol were observed in two experiments.[Results] The mouse were drenchedwith extracts of kusnezoff monkshood leaf with 50, 100 and 150·kg-1·d-1 respectively, while another experiment showed that the swellingof auricle caused by dimethyl benzene was inhibited obviously (P<0.01) and showed that the formation of granulation tumor in mousecaused by cotton ball was inhibited (P<0.01, P<0.05).[Conclusion] The result showed extracts of usnezoff monkshood leaf extracted withchloroform and n-butanol had anti-inflammatory effects.

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