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| Clinical observation on Jiawei Sinisan in treating depression after ischemic stroke |
| Hits 1429 Download times 1657 Received:October 20, 2008 |
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| DOI
10.11656/j.issn.1672-1519.2009.02.10 |
| Key Words
ischemic stroke;depression;JWSNS |
| Author Name | Affiliation | | YANG Ying-min | Wenzhou TCM Hospital of Zhejiang University of TCM, Wenzhou 325000, China |
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| Abstract
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| [Objective] To observe the clinical effect of Jiawei Sinisan (Modified Sinisan,JWSNS) on treating depression after ischemic stroke. [Methods] Eighty-seven patients of ischemic stroke with depression were randomly divided into treatment group and control group. In conventional medical treatment,44 patients of the treatment group were given JWSNS decoction orally,43 patients of control group were given oral fluoxetine hydrochloride. The clinical symptoms,signs,HAMD Scale score,the degree of neurological deficit score changes as well as the number of patients with adverse reactions after using drugs and so on were compared. [Results] The total effective rate of treatment group was 90.9% and that of control group was 74.4%. The total effective rate of treatment group was significantly higher than that of control (P<0.01). The HAMD Scale score and the degree of neurological deficit score of treatment group was significantly reduced compared with that of control group (P<0.01),and the decline in the treatment group was more obvious when compared with control (P<0.05 or P<0.01). The adverse reactions weren’t be found in treatment group. [Conclusion] JWSNS has a significant curative effect on treating depression after ischemic stroke. |
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