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Influence of Buyang Huanwu Decoction on agents of pre-thrombus state in patients with chronic cerebral circulation insufficiency
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DOI   10.11656/j.issn.1672-1519.2009.03.07
Key Words   Chronic cerebral circulation insufficiency;Pre-thrombus state;Buyang Huanwu decoction
Author NameAffiliation
CUI Jian-xiang The Second Hospital in Tongzhou, Beijing 101102, China 
DU Zhi-gang The Second Hospital in Tongzhou, Beijing 101102, China 
LI Hui The Second Hospital in Tongzhou, Beijing 101102, China 
赵宝伶 The Second Hospital in Tongzhou, Beijing 101102, China 
张学华 The Second Hospital in Tongzhou, Beijing 101102, China 
Abstract
    [Objective] To study the influence of Buyang Huanwu decoction on the agents of Pre-thrombus state in patients with chronic cerebral circulation insufficiency(CCCI). [Methods] Ninety patients with CCCI were randomly divided into 3 groups:control group,Buyang Huanwu decoction group and combined treatment group. The variation of the levels of NO,ET-1,FIB,PAI-1,t-PA was observed 3 months after treatment. [Results] In B and C groups,the NO and t-PA level were significantly higher than before,but ET-1,FIB and PAI 1 level were significantly lower. There were no statistical differences between B and C group(P>0.05). Compared with control group,there were statistical differences in both B and C groups(P<0.05). [Conclusion] Buyang Huanwu decoction can improve Pre-thrombus state in patients with CCCI. It can be considered as a therapeutic method for primary prevention of cerebral thrombosis.

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