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| Effect of Traditional Chinese Medicine Tangfukang on ICAM-1 in rats with early diabetic nephropatly |
| Hits 1575 Download times 1469 Received:March 22, 2009 |
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| DOI
10.11656/j.issn.1672-1519.2009.04.25 |
| Key Words
diabetic nephropathy;ICAM-1;Traditional Chinese Medicine Tangfukang |
| Author Name | Affiliation | | CHEN Jin-song | Tianjin First Hospital, Tianjin 300232, China | | ZHANG Bai-lin | Tianjin First Hospital, Tianjin 300232, China |
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| Abstract
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| [Objective] To discuss the effect of Tangfukang in declining the expression of ICAM-1 in rats with early diabetic nephropatly. [Methods] The rats were fed with Tangfukang, 3.5g/kg/d or 7.5g/kg/d. In the 12th week, the 12 hours urine of the rats was collected with the metabolic cage, the cardiac blood samples and the two kidneys were obtained and then the rats were killed. [Results] The high dose Tangfukang could decreased ICAM-1 of rats with early diabetic nephropatly (P<0.001). [Conclusion] Tangfukang capsule can remarkably improve the effect of the chemotaxis, adherence factor to the development of DN. |
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