|
| Effect of combined bis (α-furan carboxylato) oxovanadium (VO-FA) and Liuweidihuangwan (LW) on blood glucose and fats in rats with diabetes mellitus |
| Hits 1567 Download times 9104 Received:February 25, 2009 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2009.04.26 |
| Key Words
VO-FA combining with LW;DM;blood glucose;blood fats;empirical study |
| Author Name | Affiliation | | YANG Lin | The Department of Experimental Teaching of Tianjin University of TCM, Tianjin 300193, China | | FENG Li | Department of Pathology of Tianjin University of TCM, Tianjin 300193, China | | XU Qian | The Department of Experimental Teaching of Tianjin University of TCM, Tianjin 300193, China | | 卢斌 | The Department of Experimental Teaching of Tianjin University of TCM, Tianjin 300193, China | | 范英昌 | Department of Pathology of Tianjin University of TCM, Tianjin 300193, China | | 张柏丽 | The Department of Experimental Teaching of Tianjin University of TCM, Tianjin 300193, China |
|
| Abstract
|
| [Objective] To observe the effect of the VO-FA combining with LW on blood glucose and fats in rats with diabetic mellitus (DM). [Methods] Two different dose of combined VO-FA and LW in the DM rats induced by alloxan injection into the rats’ vena caudalis were given and the normal group and the model group were established. The change of the rats’blood glucose and fats was detected. [Results] Compared to the model group, VO-FA combining with LW could lower the blood glucose (P<0.05), and all those effects were more significantly in the higher dosage of the VO-FA combining with LW (P<0.01). The blood fats changed in the model of the DM rats. Comparing to the model group, the VO-FA combining with LW could decline the total cholesterol level especially (P<0.01), and other indicators had no significant change. [Conclusion] VO-FA combining with LW can decline the blood glucose of the DM rats’ dosedependently. It can also decline the total cholesterol level. The pharmacological mechanism will be researched further. |
|
|
|
|
|
|
|
