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| Significance of animal model of combined disease and syndrome in TCM research and new train of thoughts in establishing models |
| Hits 1652 Download times 1766 Received:June 24, 2009 |
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| DOI
10.11656/j.issn.1672-1519.2009.06.03 |
| Key Words
syndrome animal model;animal model of combined disease and syndrome;research meaning;methods for model producing |
| Author Name | Affiliation | | CUI Yi-fan | College of Fundamental Medicine, Beijing University of TCM, Beijing 100029, China | | WANG Qing-guo | College of Fundamental Medicine, Beijing University of TCM, Beijing 100029, China |
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| Abstract
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| The animal model of syndrome had significance in studying traditional Chinese medical (TCM) syndrome and TCM pharmacology. Its lagging already became the bottleneck of TCM modernization. At present, animal model of combined disease and syndrome is the most suitable technological platform for TCM research. In order to ensure objectivity of the illness cases brought into research, we should establish TCM syndrome criteria by epidemiological methods. Taking this as standard, a kind of animal model should be selected, which coincides with the clinic situation of the patients. Then, we should evaluate reliability of this animal model by demonstrating the curative effect. This thought and method was not only guided by TCM theory and verified by experimental methods. It might be the basis of disease experimental research and evaluating the clinic effect of TCM. |
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