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| Effect of asparagus polysaccharide on components and floating characteristics of erythrocyte membrane in S180 mice |
| Hits 1543 Download times 1831 Received:September 16, 2009 |
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| DOI
10.11656/j.issn.1672-1519.2009.06.16 |
| Key Words
asparagus polysaccharide;erythrocyte;membrane floating characteristics |
| Author Name | Affiliation | | JI Chen-feng | School of Materia Mediea, Beijing University Of TCM, Beijing 100102, China
Engineering Reseach Center of Natural Anticancer Drugs, Ministry of Education, Harbin 150076, China
Center of Research on Life Sciences and Environmental Sciences, Harbin 150076, China | | 季宇彬 | Engineering Reseach Center of Natural Anticancer Drugs, Ministry of Education, Harbin 150076, China
Center of Research on Life Sciences and Environmental Sciences, Harbin 150076, China
Institute of Materia Medica and Postdoctoral Program of Harbin University of Commerce, Harbin 150076, China |
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| Abstract
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| [Objective] To study the effect of asparagus polysaccharide on membrane components and floating characteristics of erythrocyte in S180 mice. [Methods] S180 mice were administrated with asparagus polysaccharide i.p. for 7 days and we determined band 3 protein and glycophorin a content by SDS-PAGE, membrane phspholipid, cholesterol and sialic acid with test kit, the floating characteristics of membrane with fluorescence polariscopy combined with DPH. [Results] It was showed that asparagus polysaccharide could increase band 3 protein and glycophorin a content on erythrocyte membrane, increased phospholipids content and decreased cholesterol content, in creased sialic acid content, adjust membrane floating characteristics. [Conclusion] Asparagus polysaccharide can adjust the abnormality of S180 mice, and improve membrane floating characteristics, restore erythrocyte membrane structure and function. |
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