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| The effect of Shugandaozhuo medicine on AST,ALT,ALP,NO,SOD and MDA in rabbit with fatty liver |
| Hits 1748 Download times 1888 Received:October 27, 2009 |
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| DOI
10.11656/j.issn.1672-1519.2010.01.05 |
| Key Words
fatty liver;Shugandaozhuo Medicine;SOD;AST;ALT;ALP;NO;MDA |
| Author Name | Affiliation | | WANG Wei | Tianjin University of TCM, Tianjin 300193, China | | JIANG Hai-tao | Tianjin University of TCM, Tianjin 300193, China | | SHI Hong | Tianjin University of TCM, Tianjin 300193, China | | 刘友刚 | Tianjin University of TCM, Tianjin 300193, China | | 王超 | Tianjin University of TCM, Tianjin 300193, China | | 田维 | Tianjin University of TCM, Tianjin 300193, China | | 胡利民 | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To observe the effects of Shuogandaozhuo Medicine (dispersing stagnation of liver-Q and reducing the turbid pathogen,SM) on liver function and its anti-oxygenation in rabbits with fatty liver.[Methods] The fatty liver in rabbits was induced by feeding them with high caloric diet for six weeks.Sixty rabbits were randomly divided into six groups including the high-dose,middledose and low-dose SM groups,the Dongbaogantai group,the model group and the normal control group.The liver index (liver weight/body weight),the amount of AST,ALT,ALP,NO,SOD and MDA in the serum were investigated after medication.[Results] The liver function and the amount of SOD decreased significantly (P<0.05) in the model group with significant increasing of the MDA (P<0.01);Significant increase of SOD was found in the middle and low-dose of the SM group (P<0.05).[Conclusion] SM is effective for increasing anti-oxidation in rabbits with fatty liver. |
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