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Clinical study on the therapy for acute cerebral infarction with Huatan Tongluo combined with urokinase thrombolysis
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DOI   10.11656/j.issn.1672-1519.2010.01.06
Key Words   acute cerebral infarction;Huatan Tongluo;thrombolysis;clinical study
Author NameAffiliation
ZHANG Yu-lian The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300150, China 
ZHOU zhen The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300150, China 
GUO Jia-kui The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300150, China 
张连城 The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300150, China 
王占奎 The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300150, China 
崔远武 The Second Hospital Affiliated to Tianjin University of TCM, Tianjin 300150, China 
Abstract
    [Objective] To evaluate the therapeutic effect of the of Chinese medicine combined with urokinase on acute cerebral infarction.[Methods] Based on the enrolled criteria sixty patients with acute cerebral infarction were randomly divided into the experiment and the control groups.Both groups were continuously given urokinase for three days.After that,the Huatan Tongluo (resolving phlegm and dredging collateral) medication was administered only in the experiment group for 14 days one dose a day.The NIHSS,Barthel Index(BI)and modified Rankin Scale (mRS) were analyzed for all subjects.[Results] The experiment group showed superiority in improving the scores of NIHSS and Barthel index compared to the control group (P<0.05);Based on the evaluating of MRS the experiment group was superior to the control group although no significant statistic difference was found (P>0.05).[Conclusion] The Huatan Tongluo combined with urokinase can improve the neural function and the living quality of the patients with cerebral infarction.It is believed that the Chinese medicine combined with urokinase is effective on patients with acute cerebral infarction and is superior to the therapy of urokinase only.

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