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The therapeutic effects of Qixiong Jianshen Granula on mesangial proliferative glomerulonephritis |
Hits 1646 Download times 1872 Received:October 26, 2009 |
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DOI
10.11656/j.issn.1672-1519.2010.01.29 |
Key Words
Qixiong Jianshen granule;invigorating the spleen and kidney;promoting blood flow and detumescence;mesangial proliferative glomerulonephritis;rats;experiment research |
Author Name | Affiliation | HUO Shu-jie | Huabei Coal Medical College, Hebei, Tangshan 063000, China | ZHAO Ren | Tangshan TCM Hospital, Hebei, Tangshan 063000, China |
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Abstract
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[Objective] To study the therapeutic effects of Qixiong Jianshen granule on mesangial proliferative glomerulonephritis (MsPGN).[Methods] The rat model of MsPGN was established.The quantitative urine protein in 24 hours,renal function and renal pathological changes were observed.[Results] The groups treated by low or high dose of Qixiong Jianshen granule showed decreased urine protein,serum creatinine (SCR),blood urea nitrogen (BUN) and proliferation of MC,and increased EMC.[Conclusion] Qixiong Jianshen granule is effective for MsPGN. |
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