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The therapeutic effects of Qixiong Jianshen Granula on mesangial proliferative glomerulonephritis
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DOI   10.11656/j.issn.1672-1519.2010.01.29
Key Words   Qixiong Jianshen granule;invigorating the spleen and kidney;promoting blood flow and detumescence;mesangial proliferative glomerulonephritis;rats;experiment research
Author NameAffiliation
HUO Shu-jie Huabei Coal Medical College, Hebei, Tangshan 063000, China 
ZHAO Ren Tangshan TCM Hospital, Hebei, Tangshan 063000, China 
Abstract
    [Objective] To study the therapeutic effects of Qixiong Jianshen granule on mesangial proliferative glomerulonephritis (MsPGN).[Methods] The rat model of MsPGN was established.The quantitative urine protein in 24 hours,renal function and renal pathological changes were observed.[Results] The groups treated by low or high dose of Qixiong Jianshen granule showed decreased urine protein,serum creatinine (SCR),blood urea nitrogen (BUN) and proliferation of MC,and increased EMC.[Conclusion] Qixiong Jianshen granule is effective for MsPGN.

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