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Effect of Huoxue Huayu plaster on NO and MMP-13 in joint fluid of osseous arthritis of knee in the early and middle stage |
Hits 2201 Download times 1883 Received:January 20, 2010 |
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DOI
10.11656/j.issn.1672-1519.2010.03.09 |
Key Words
Huoxue Huayu Plaster;osseous arthritis of knee;NO;MMP-13 |
Author Name | Affiliation | WANG Ping | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | GU EN-peng | The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China | CAO HONG-yu | Graduated College of Tianjin University of TCM, Tianjin 300193, China |
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Abstract
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[Objective] To study the effect of Huoxue Huayu plaster on NO and MMP-13 level in osseous arthritis of knee in the early and middle stage and the clinical therapeutic action taking voltaren emulsion as control.[Methods] Sixty cases with early and middle stage of osseous arthritis of knee were randomly divided into two groups:treatment and control groups.they were treated by huoxuehuayu Plaster and Voltaren respectively.One or two weeks later the HSS score,pain score,content of NO and MMP-13 were observed [Results] There was a significant difference in the HSS Scale total score,pain points and NO content between treating for 1 and 2 weeks and the condition before treatment(P<0.05).[Conclusion] The Huoxue Huayu Plaster can improve knee function and enhance stability. |
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