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| Observation on haemorheology in rats with blood stasis induced by cold coagulation and pyretic toxicity and intervention effect of the Traditional Chinese Medicine |
| Hits 1786 Download times 2194 Received:March 28, 2010 |
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| DOI
10.11656/j.issn.1672-1519.2010.03.34 |
| Key Words
decoction for regulating menstruation;decoction for clearing heat in nutrient system;blood stasis syndrome;animal model;high blood stagnation;rheology of blood |
| Author Name | Affiliation | | WANG Xue-ling | Clinical Teaching Department of Practice Training of Tianjin University of TCM, Tianjin 300193, China | | LU Yi-zhu | Clinical Teaching Department of Practice Training of Tianjin University of TCM, Tianjin 300193, China | | CAI Yi-ling | 天津中医药大学第一附属医院, 天津, 300193 | | 蔡琦玲 | Tianjin University of TCM, Tianjin 300193, China | | 韩耀巍 | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To observe the effect of Wenjing decoction and Qingying decoction on the rheologic changes in rats with blood stasis and study its intervention function against blood stagnation.[Methods] Eighty SD rats were randomly divided into five groups.They were treated with corresponding treatment after the disease was established successfully.The rats of blank control group weren’t given any treatment.The whole blood viscosity,RBC aggregation index,hematocrit were then observed.[Results] The whole blood viscosity,the RBC aggregation index and hematocrit of the rats were raised evidently in each group.The difference in change of the whole blood viscosity,the RBC aggregation index and hematocrit between the blank control group,the herbal medicine group and the blood stasis group were obvious and had statistical significance(P<0.01 or P<0.05).[Conclusion] The above results indicate that Wenjing and Qingying decoction can decrease the blood viscosity in rats with blood stasis.The mechanism of blood stasis syndrome was relative to the change of rheology of blood.The experiment has provided the theory and experimental basis for diagnosis and treatment of corresponding diseases. |
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