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| Effects of dahuang huoling decoction on the expression of bFGF in rats with chronic renal failure |
| Hits 2022 Download times 2150 Received:January 10, 2010 |
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| DOI
10.11656/j.issn.1672-1519.2010.03.35 |
| Key Words
Dahuang Huoling decoction;adenine;CRF;bFGF |
| Author Name | Affiliation | | HAN Shun-ping | Tianjin University of TCM, Tianjin 300193, China | | YANG You-xin | Tianjin University of TCM, Tianjin 300193, China | | YUAN Chao-sheng | The PLA 272 Hospital, Tianjin 300020, China | | 杨曼 | The PLA 272 Hospital, Tianjin 300020, China | | 马艳 | Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objection] To explore the protective function and of Dahuang Huoling decoction on rats with chronic renal failure.[Methods] To establish the rats model by using adenine,divide the model rats into normal group,model group,medicated group 1 and medicated group 2.[Results] The pathology changes of the medicated group 1 and 2 were lighter than that of the control group.Blood Urea Nitrogen(BUN),creatinine,uric acid and bFGF expressions of medicated group 1 were lower than that of the model group(P<0.05).The bFGF expressions in medicated group 2 were no obviously differentiation than that in model group(P>0.05).[Conclusion] Dahuang Huoling decoction had protective function on chronic renal failure of rat kidney caused by adenine.Early medication was more effective than later period.Its mechanism can be the restraint in bFGF expressions. |
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